Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92088 | 0.91 | LMNA (0.46) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL31565026 | 0.91 | LMNA (0.46) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| Nitrous Acid SCHEMBL6396175 | 0.87 | LMNA (0.43) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Nitrous Acid SCHEMBL6396171 | 0.87 | LMNA (0.43) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL13033693 | 0.86 | STAT3 (0.51) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL14395720 | 0.83 | CYP1A2 (0.58) | SMN1; SMN2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL13969947 | 0.82 | MAPT (0.53) | L3MBTL1KMT2AMAPTPPARGPPARA | |
| SCHEMBL212829 | 0.82 | MAPT (0.53) | L3MBTL1KMT2AMAPTPPARGPPARA | |
| SCHEMBL13567344 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL7296406 | 0.80 | MAPT (0.53) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687220-B2 | Oxime derivatives and use thereof as latent acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20080085458-A1 | Oxime Derivatives And Use Thereof As Latent Acids | CIBA SPECIALTY CHEMICALS CORPORATION | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085458-A1 | Oxime Derivatives And Use Thereof As Latent Acids | ARSA, CYP2S1, QSOX1 | SMN1; SMN2 3989/4885CASP3 2417/4885SENP8 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.