SCHEMBL1346256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1347014	0.93	MAOA (0.55)	MAOAMAOBCA1CA9CA12
	SCHEMBL4811875	0.83	PBRM1 (0.41)	MAOAMAOBBRD4PTGS2PBRM1
	SCHEMBL1346659	0.81	MAOB (0.48)	MAOBCA1CA9CA12MEN1
	SCHEMBL1345772	0.79	MAOB (0.42)	MAOAMAOBCA1CA9CA12
	SCHEMBL18289524	0.79	CA1 (0.50)	CA1CA9CA12ALDH1A1CA2
	SCHEMBL6906905	0.79	CA1 (0.50)	CA1CA9CA12ALDH1A1CA2
	SCHEMBL8207005	0.77	CA1 (0.41)	CA1CA9CA12ALDH1A1CA2
	SCHEMBL18289526	0.77	CYP19A1 (0.50)	CA1CA9CA12VDRCA2
	SCHEMBL13748706	0.76	PNMT (0.51)	—
	SCHEMBL6823960	0.75	CA1 (0.45)	CA1CA9CA12PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.