Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583214 | 0.95 | PIK3CD (0.44) | SIRT2SIRT1MAPTPIK3CDGRM2 | |
| SCHEMBL20695806 | 0.77 | KDM4E (0.44) | MAPTGRM2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL27834661 | 0.76 | MAPT (0.68) | SIRT2SIRT1MAPTKDM4EALDH1A1 | |
| SCHEMBL14537170 | 0.75 | MAPK1 (0.56) | SIRT2SIRT1MAPTALDH1A1POLB | |
| SCHEMBL2578048 | 0.75 | SIRT2 (0.41) | SIRT2SIRT1MAPTGRM2KDM4E | |
| SCHEMBL2581182 | 0.73 | ACHE (0.48) | SIRT2SIRT1KDM4EALDH1A1POLB | |
| SCHEMBL9016265 | 0.73 | GRM2 (0.56) | MAPTPIK3CDGRM2KDM4EALDH1A1 | |
| SCHEMBL14403257 | 0.72 | ALDH1A1 (0.67) | SIRT2SIRT1MAPTKDM4EALDH1A1 | |
| SCHEMBL514643 | 0.72 | SIRT2 (0.42) | SIRT2SIRT1GRM2 | |
| SCHEMBL5584770 | 0.71 | MPO (0.51) | SIRT2SIRT1MAPTGRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026989-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | 日産化学工業株式会社 (JP) | 2010-03-11 | — | — | WO | disclosed |