SCHEMBL134644

SCHEMBL134644

O=C(Cc1ccc(O)cc1)Nc1ncc(-c2ccc(O)cc2)nc1Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.49
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
TMIGD3 P0DMS9 1/20 0.46
ABCB1 P08183 1/20 0.46
ELOVL1 Q9BW60 1/20 0.44
MTOR P42345 1/20 0.43
ROCK1 Q13464 2/20 0.43
MAOB P27338 1/20 0.43
PRKDC P78527 1/20 0.43
ATM Q13315 1/20 0.43
ATR Q13535 1/20 0.43
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
GLS O94925 1/20 0.42
WNT3A P56704 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1354289 0.99 DEGS1 (0.50) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12839941 0.98 DEGS1 (0.49) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838880 0.95 KMT2A (0.46) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838882 0.95 DEGS1 (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838890 0.95 DEGS1 (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838494 0.95 KMT2A (0.46) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838881 0.95 DEGS1 (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12839658 0.95 DEGS1 (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL15343487 0.93 MCL1 (0.43) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL15343485 0.92 APP (0.51) MEN1KMT2ANPC1RAB9AMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 973 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10156557-B2 Calcium-binding photoprotein JNC CORPORATION (JP) 2018-12-18 US claimed
US-9678067-B2 Method for extending light-emitting time of calcium-binding photoprotein solution JNC CORPORATION (JP) 2017-06-13 US claimed
US-20140329250-A1 CALCIUM-BINDING PHOTOPROTEIN JNC CORP (JP) 2014-11-06 US claimed
US-8816052-B2 Mutant apoprotein of photoprotein with low calcium sensitivity JNC CORPORATION (JP) 2014-08-26 US claimed
US-8710195-B2 Fluorescent proteins JNC CORPORATION (JP) 2014-04-29 US claimed
US-20120258465-A1 MUTANT APOPROTEIN OF PHOTOPROTEIN WITH LOW CALCIUM SENSITIVITY JNC CORPORATION (JP) 2012-10-11 US claimed
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US claimed
US-20100311051-A1 Calcium-binding photoprotein, gene encoding the same and use thereof CHISSO CORPORATION 2010-12-09 US claimed
EP-1666488-B1 FLUORESCENT PROTEIN CHISSO CORP (JP) 2010-11-17 EP claimed
US-7396655-B2 Method for enhancing activity of luciferase with fluorescence activity CHISSO CORPORATION (JP) 2008-07-08 US claimed
US-20060234324-A1 Method for enhancing activity of luciferase with fluorescence activity CHISSO CORPORATION (JP) 2006-10-19 US claimed
US-20060044781-A1 Bioluminescent fog for military and law enforcement ADVANCED ENERGY INDUSTRIES, INC. 2006-03-02 US claimed
US-12630492-B2 Cannabinoid derivatives CANOPY GROWTH CORPORATION (CA) 2026-05-19 US disclosed
EP-4731219-A2 COMPOUNDS AND METHODS OF USE THEREOF FOR ASSESSING TARGET ENGAGEMENT FOR DNA POLYMERASE THETA Promega Corporation (US) 2026-04-29 EP disclosed
US-12596119-B2 Analyte detection immunoassay PROMEGA CORPORATION (US) 2026-04-07 US disclosed
US-20260028662-A1 OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE PROMEGA CORP (US) 2026-01-29 US disclosed
WO-1997029319-A2 BIOLUMINESCENT NOVELTY ITEMS BRYAN BRUCE J (US) 1997-08-14 WO disclosed
EP-0721509-A1 FERTILE, TRANSGENIC MAIZE PLANTS AND METHODS FOR THEIR PRODUCTION DeKalb Genetics Corporation (US) 1996-07-17 EP disclosed
WO-1995006128-A9 FERTILE, TRANSGENIC MAIZE PLANTS AND METHODS FOR THEIR PRODUCTION 1995-03-30 WO disclosed
WO-1995006128-A2 FERTILE, TRANSGENIC MAIZE PLANTS AND METHODS FOR THEIR PRODUCTION DEKALB GENETICS CORPORATION (US) 1995-03-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630492-B2 Cannabinoid derivatives CNR2, CNR1, OPRM1 DEGS1 226/4885MEN1 2519/4885KMT2A 210/4885
US-20060234324-A1 Method for enhancing activity of luciferase with fluorescence activity CACYBP, PRCP, GBA3 DEGS1 4828/4885MEN1 3437/4885KMT2A 2996/4885
US-12596119-B2 Analyte detection immunoassay FEM1B, CTNNBL1, GSKIP DEGS1 4863/4885MEN1 3331/4885KMT2A 3267/4885
US-20140329250-A1 CALCIUM-BINDING PHOTOPROTEIN CACYBP, ORAI2, ITPR2 DEGS1 3991/4885MEN1 4162/4885KMT2A 2998/4885
US-20260028662-A1 OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE RNGTT, VIP, PREP DEGS1 3672/4885MEN1 3446/4885KMT2A 3368/4885
US-10156557-B2 Calcium-binding photoprotein CACYBP, ORAI2, ITPR2 DEGS1 3991/4885MEN1 4162/4885KMT2A 2998/4885
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 DEGS1 4476/4885MEN1 3926/4885KMT2A 4653/4885
US-20100311051-A1 Calcium-binding photoprotein, gene encoding the same and use thereof CACYBP, ORAI2, CIB1 DEGS1 4277/4885MEN1 4069/4885KMT2A 3236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.