Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 11/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186762 | 0.80 | PTGS1 (0.62) | TSHRALDH1A1POLBPTGS1KMT2A | |
| SCHEMBL10270716 | 0.79 | ALDH1A1 (0.47) | MRGPRX1TSHRALDH1A1PTGS1PTGS2 | |
| SCHEMBL23014672 | 0.78 | PGAM1 (0.49) | MRGPRX1ALDH1A1POLBPTGS1PTGS2 | |
| SCHEMBL25996431 | 0.76 | CKS1B (0.48) | MRGPRX1PTGS1PTGS2TSPO | |
| SCHEMBL14830962 | 0.75 | TSHR (0.47) | MRGPRX1TSHRPOLBPTGS1PTGS2 | |
| SCHEMBL29739977 | 0.75 | PTGS1 (0.47) | MRGPRX1PTGS1PTGS2 | |
| SCHEMBL22290162 | 0.75 | PTGS1 (0.47) | MRGPRX1PTGS1PTGS2 | |
| SCHEMBL14830870 | 0.75 | PSIP1 (0.53) | MRGPRX1TSHRPOLBPTGS1PTGS2 | |
| SCHEMBL2737229 | 0.75 | L3MBTL1 (0.67) | MRGPRX1ALDH1A1POLBPTGS1PTGS2 | |
| SCHEMBL24498308 | 0.74 | TDP1 (0.46) | MRGPRX1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012139891-A1 | SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2012-10-18 | — | — | WO | disclosed |