Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13476274 | 0.94 | ALDH1A1 (0.33) | ALDH1A1USP2LMNATSHRKDM4E | |
| SCHEMBL13476248 | 0.93 | ALDH1A1 (0.35) | ALDH1A1USP2LMNATSHRKDM4E | |
| SCHEMBL12428662 | 0.86 | SCN9A (0.39) | ALDH1A1USP2LMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL773003 | 0.86 | SCN9A (0.38) | ALDH1A1USP2LMNATSHRKDM4E | |
| SCHEMBL12428583 | 0.83 | PRKCA (0.41) | ALDH1A1USP2LMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL771907 | 0.83 | PRKCA (0.41) | ALDH1A1USP2LMNATSHRKDM4E | |
| SCHEMBL13476320 | 0.80 | FFAR4 (0.32) | ALDH1A1MAOB | |
| SCHEMBL10252741 | 0.80 | SCN9A (0.37) | ALDH1A1USP2LMNATSHRKDM4E | |
| SCHEMBL12428671 | 0.80 | TRPM8 (0.34) | ALDH1A1USP2LMNATSHRCA12 | |
| Hydrochloric Acid SCHEMBL771301 | 0.79 | TRPM8 (0.34) | ALDH1A1USP2LMNATSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659263-B2 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-02-09 | — | — | US | disclosed |
| US-7659263-B2 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-02-09 | — | — | US | disclosed |