Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445966 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL12758194 | 0.74 | HPGD (0.45) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL2806467 | 0.69 | LMNA (0.40) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL2806471 | 0.69 | LMNA (0.40) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL21128882 | 0.68 | MEN1 (0.34) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| Malonic Acid SCHEMBL2415013 | 0.67 | LMNA (0.39) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL12101244 | 0.67 | MEN1 (0.38) | ALDH1A1KMT2AHPGDMAPTMEN1 | |
| SCHEMBL14221248 | 0.66 | MAPT (0.32) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL13398977 | 0.66 | — | — | |
| SCHEMBL1576555 | 0.66 | LMNA (0.37) | ALDH1A1KDM4EKMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9068080-B2 | Merocyanine derivatives | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9068080-B2 | Merocyanine derivatives | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20100035839-A1 | MEROCYANINE DERIVATIVES | CIBA CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035839-A1 | MEROCYANINE DERIVATIVES | C1R, MC5R, C2CD5 | ALDH1A1 1702/4885KDM4E 3106/4885KMT2A 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.