SCHEMBL17445966

SCHEMBL17445966

CCCCNC(=O)C(C#N)=CC=C1OCC(C)(C)N1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.44
▸ HPGD P15428 5/20 0.44
▸ LMNA P02545 5/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ TP53 P04637 1/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ PKM P14618 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ GAA P10253 2/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ MITF O75030 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ EGFR P00533 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13485630 0.86 ALDH1A1 (0.33) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL12758194 0.85 HPGD (0.45) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL21128882 0.75 MEN1 (0.34) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL14221248 0.73 MAPT (0.32) ALDH1A1LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL13419346 0.70 — —
SCHEMBL17445965 0.69 PRKCA (0.33) ALDH1A1HPGDLMNAATMSMN1; SMN2
SCHEMBL13398992 0.69 — —
SCHEMBL21128883 0.65 GLO1 (0.38) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL10601780 0.65 SMN1; SMN2 (0.44) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL14254898 0.65 SMN1; SMN2 (0.44) ALDH1A1HPGDLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518031-B2 Photo-sensitive resin composition, cured film, method for forming a pixel, solid state image sensor, color filter and ultraviolet absorber FUJIFILM CORPORATION (JP) 2016-12-13 — — US disclosed
US-9518031-B2 Photo-sensitive resin composition, cured film, method for forming a pixel, solid state image sensor, color filter and ultraviolet absorber FUJIFILM CORPORATION (JP) 2016-12-13 — — US disclosed
US-9481657-B2 — — 2016-11-01 — — US disclosed
US-9481657-B2 — — 2016-11-01 — — US disclosed
US-20160016919-A1 PHOTO-SENSITIVE RESIN COMPOSITION, CURED FILM, METHOD FOR FORMING A PIXEL, SOLID STATE IMAGE SENSOR, COLOR FILTER AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2016-01-21 — — US disclosed
US-20160016919-A1 PHOTO-SENSITIVE RESIN COMPOSITION, CURED FILM, METHOD FOR FORMING A PIXEL, SOLID STATE IMAGE SENSOR, COLOR FILTER AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2016-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016919-A1 PHOTO-SENSITIVE RESIN COMPOSITION, CURED FILM, METHOD FOR FORMING A PIXEL, SOLID STATE IMAGE SENSOR, COLOR FILTER AND ULTRAVIOLET ABSORBER STRA6, TAS2R7, TAS1R3 ALDH1A1 3737/4885HPGD 3926/4885LMNA 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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