Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806471 | 1.00 | LMNA (0.40) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| Malonic Acid SCHEMBL2415013 | 0.97 | LMNA (0.39) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1576555 | 0.95 | LMNA (0.37) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL12496025 | 0.95 | LMNA (0.37) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL14488715 | 0.83 | CES2 (0.34) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2409914 | 0.83 | PTAFR (0.35) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL2409916 | 0.83 | PTAFR (0.35) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4851098 | 0.83 | DNM1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4851091 | 0.83 | DNM1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14018852 | 0.83 | DNM1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683351-B1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |
| EP-2266531-B1 | Cosmetic composition comprising a superabsorbent polymer and an organic UV filter | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-2538914-B1 | COSMETIC COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND AT LEAST A GEMINI SURFACTANT | ORÉAL L (FR) | 2016-06-15 | — | — | EP | disclosed |
| US-9364690-B2 | Composition comprising a superabsorbent polymer and a gemini surfactant | L'OREAL (FR) | 2016-06-14 | — | — | US | disclosed |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20150224046-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | L'OREAL (FR) | 2015-08-13 | — | — | US | disclosed |
| EP-2482793-B1 | USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | ORÉAL L (FR) | 2015-04-22 | — | — | EP | disclosed |
| US-8716311-B2 | Use of piperidine ester derivative as solvent in cosmetic compositions; cosmetic compositions comprising it | L'OREAL (FR) | 2014-05-06 | — | — | US | disclosed |
| US-20140056832-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | L'OREAL (FR) | 2014-02-27 | — | — | US | disclosed |
| US-20130039963-A1 | COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND A GEMINI SURFACTANT | L'OREAL (FR) | 2013-02-14 | — | — | US | disclosed |
| US-20120269746-A1 | USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-20100330018-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | L'OREAL (FR) | 2010-12-30 | — | — | US | disclosed |
| EP-2266531-A1 | Cosmetic composition comprising a superabsorbent polymer and an organic UV filter | L'Oréal (FR) | 2010-12-29 | — | — | EP | disclosed |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | L'OREAL (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-2193783-A1 | Use of an ester derived from 4-carboxy-2-pyrrolidinone as a solvent in cosmetic compositions; cosmetic compositions containing same | L'Oreal (FR) | 2010-06-09 | — | — | EP | disclosed |
| US-7439380-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-21 | — | — | US | disclosed |
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL | 2007-09-13 | — | — | US | disclosed |
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | LMNA 938/4885SMN1; SMN2 1365/4885KDM4E 2378/4885 |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | LMNA 938/4885SMN1; SMN2 1365/4885KDM4E 2378/4885 |
| US-20140056832-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | DIMT1, MAT2A, SCD | LMNA 2896/4885SMN1; SMN2 2328/4885KDM4E 591/4885 |
| US-20150224046-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | KRT18, FABP2, FABP4 | LMNA 1156/4885SMN1; SMN2 4685/4885KDM4E 3344/4885 |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | DIMT1, FADS2, SCD | LMNA 2770/4885SMN1; SMN2 2411/4885KDM4E 591/4885 |
| US-20100330018-A1 | COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT | KRT18, FABP2, FABP4 | LMNA 1156/4885SMN1; SMN2 4685/4885KDM4E 3344/4885 |
| US-20120269746-A1 | USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT | DEGS1, CAPN1, PPT1 | LMNA 274/4885SMN1; SMN2 3359/4885KDM4E 3150/4885 |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | FASN, ALOX12, PAH | LMNA 461/4885SMN1; SMN2 3473/4885KDM4E 148/4885 |
| US-20130039963-A1 | COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND A GEMINI SURFACTANT | SGMS2, SGMS1, SCO2 | LMNA 2477/4885SMN1; SMN2 2010/4885KDM4E 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.