SCHEMBL13488484

SCHEMBL13488484

CC(C)On1nnc2cccnc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.39
MGLL Q99685 3/20 0.39
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36
TUBB2B Q9BVA1 1/20 0.36
TUBB1 Q9H4B7 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757020 0.83 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL18392721 0.82 FAAH (0.39) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL798141 0.81 FAAH (0.41) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL22898718 0.78 ALDH1A1 (0.38) FAAHMGLLALDH1A1MEN1KMT2A
SCHEMBL15998529 0.78 FAAH (0.34) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL1984416 0.78 TUBB4A (0.38) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL20626659 0.77 FAAH (0.45) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL8448754 0.77 FAAH (0.47) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL15862647 0.77 FAAH (0.39) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL15697618 0.77 FAAH (0.39) FAAHMGLLTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146945-A1 NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-11 WO disclosed
WO-2024126650-A1 NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2024115512-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed
WO-2024115509-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed
WO-2024105104-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-05-23 WO disclosed
US-11857605-B2 Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof BILLION KING INTERNATIONAL LIMITED (CN) 2024-01-02 US disclosed
US-11857605-B2 Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof BILLION KING INTERNATIONAL LIMITED (CN) 2024-01-02 US disclosed
WO-2023217989-A1 ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-11-16 WO disclosed
US-11692022-B2 Thiosuccinyl-crosslinked hemoglobin analogs and methods of use and preparation thereof BILLION KING INTERNATIONAL LIMITED (CN) 2023-07-04 US disclosed
US-11692022-B2 Thiosuccinyl-crosslinked hemoglobin analogs and methods of use and preparation thereof BILLION KING INTERNATIONAL LIMITED (CN) 2023-07-04 US disclosed
US-20210395309-A1 PEPTIDE-DRUG CONJUGATES HONG KONG BAPTIST UNIVERSITY (CN) 2021-12-23 US disclosed
WO-2021013131-A1 HEMOGLOBIN-BASED THERAPEUTIC AGENTS Cheer Global Limited (CN) 2021-01-28 WO disclosed
US-20210015935-A1 HEMOGLOBIN-BASED THERAPEUTIC AGENTS Cheer Global Limited (HK) 2021-01-21 US disclosed
WO-2020239855-A1 MICROBIOCIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2020-12-03 WO disclosed
WO-2017134547-A1 TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION PFIZER INC. (US) 2017-08-10 WO disclosed
US-20170014520-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION 2017-01-19 US disclosed
US-9469850-B2 Oligosaccharides comprising an aminooxy group and conjugates thereof GENZYME CORPORATION (US) 2016-10-18 US disclosed
US-20150050262-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION (US) 2015-02-19 US disclosed
US-8759501-B2 Oligosaccharides comprising an aminooxy group and conjugates thereof GENZYME CORPORATION (US) 2014-06-24 US disclosed
US-20100047225-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION (US) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395309-A1 PEPTIDE-DRUG CONJUGATES BDKRB1, VIP, BDKRB2 FAAH 2875/4885MGLL 4358/4885TUBB4A 1772/4885
US-11692022-B2 Thiosuccinyl-crosslinked hemoglobin analogs and methods of use and preparation thereof HBG1, HBG2, HBB FAAH 3547/4885MGLL 2849/4885TUBB4A 2034/4885
US-20150050262-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA FAAH 3163/4885MGLL 875/4885TUBB4A 1838/4885
US-20170014520-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA FAAH 3163/4885MGLL 875/4885TUBB4A 1838/4885
US-20210015935-A1 HEMOGLOBIN-BASED THERAPEUTIC AGENTS HBG1, HBG2, HBB FAAH 4625/4885MGLL 4338/4885TUBB4A 1865/4885
US-20100047225-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA FAAH 3163/4885MGLL 875/4885TUBB4A 1838/4885
US-11857605-B2 Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof HBG1, HBG2, HBB FAAH 4095/4885MGLL 3874/4885TUBB4A 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.