Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720386 | 0.77 | MAPT (0.42) | MAPTMEN1KMT2ASCN5ANOTUM | |
| SCHEMBL5325379 | 0.76 | TSHR (0.39) | ALDH1A1TSHRSMN1; SMN2HIF1AHSD17B10 | |
| SCHEMBL4404035 | 0.75 | AR (0.36) | ALDH1A1MAPTTRPA1SCN9APGR | |
| SCHEMBL6573031 | 0.75 | FFAR4 (0.40) | NOTUMKIF11 | |
| SCHEMBL2961646 | 0.74 | TSHR (0.31) | ALDH1A1MAPTMEN1TP53CYP3A4 | |
| SCHEMBL10469320 | 0.73 | SLC6A2 (0.46) | SCN5ANOTUMKIF11 | |
| SCHEMBL4463853 | 0.72 | SCN5A (0.34) | ALDH1A1MAPTSCN5ASCN9ANOTUM | |
| SCHEMBL134890 | 0.72 | KDM5A (0.37) | KDM5AALDH1A1MAPTMEN1TP53 | |
| SCHEMBL1804807 | 0.71 | AR (0.43) | PGRARKIF11 | |
| SCHEMBL3291416 | 0.71 | TRPV1 (0.46) | KDM5AALDH1A1MAPTSCN5ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116290-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | Platefuse, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| EP-4013402-A1 | METHODS OF TREATING A SUBJECT WITH A CDC42-SPECIFIC INHIBITOR | Children's Hospital Medical Center (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3999053-A1 | METHOD OF TREATING NEOPLASTIC DISEASES WITH A CDC42-SPECIFIC INHIBITOR | Children's Hospital Medical Center (US) | 2022-05-25 | — | — | EP | disclosed |
| US-20220061312-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | PLATEFUSE, INC. | 2022-03-03 | — | — | US | disclosed |
| US-11172673-B2 | Platelet storage methods and compositions for same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2021-11-16 | — | — | US | disclosed |
| WO-2021034616-A1 | METHODS OF TREATING A SUBJECT WITH A CDC42-SPECIFIC INHIBITOR | CHILDREN' S HOSPITAL MEDICAL CENTER (US) | 2021-02-25 | — | — | WO | disclosed |
| WO-2021011800-A1 | METHOD OF TREATING NEOPLASTIC DISEASES WITH A CDC42-SPECIFIC INHIBITOR | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2021-01-21 | — | — | WO | disclosed |
| US-10405538-B2 | Platelet storage methods and compositions for same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2019-09-10 | — | — | US | disclosed |
| US-20190021307-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | PLATEFUSE, INC. | 2019-01-24 | — | — | US | disclosed |
| US-10028503-B2 | Platelet storage methods and compositions for same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-07-24 | — | — | US | disclosed |
| US-20050192268-A1 | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders | ACADIA PHARMACEUTICALS INC. | 2005-09-01 | — | — | US | disclosed |
| EP-1562937-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | Acadia Pharmaceuticals Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2005063254-A2 | AMINO SUBSTITUTED DIARYL[A,D]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS | ACADIA PHARMACEUTICALS INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005059180-A1 | METHODS OF ATTACHING OLIGONUCLEOTIDES AND PEPTIDES TO SOLID SUPPORTS USING 2,4-HYDRAZIN- (1, 3, 5) TRIAZINE-ACTIVATED SOLID PHASES | ILLUMINA, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050136406-A1 | Methods of attaching biological compounds to solid supports using triazine | ILLUMINA, INC. | 2005-06-23 | — | — | US | disclosed |
| US-20050096319-A1 | Identification of compounds that inhibit replication of human immunodeficiency virus | TRIPEP AB (SE) | 2005-05-05 | — | — | US | disclosed |
| US-20040180893-A1 | enzymatically or synthetically prepared alpha-hydroxyglycinamide inhibit the replication of HIV in human serum | TRIPEP AB (SE) | 2004-09-16 | — | — | US | disclosed |
| WO-2004073703-A1 | GLYCINAMIDE DERIVATIVE FOR INHIBITING HIV REPLICATION | TRIPEP AB (SE) | 2004-09-02 | — | — | WO | disclosed |
| US-20040106600-A1 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004000808-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096319-A1 | Identification of compounds that inhibit replication of human immunodeficiency virus | GALE, ENGASE, GLMN | KDM5A 1415/4885ALDH1A1 1375/4885MAPT 3758/4885 |
| US-10405538-B2 | Platelet storage methods and compositions for same | RHOA, ARHGDIB, ARHGDIA | KDM5A 4068/4885ALDH1A1 3922/4885MAPT 1809/4885 |
| US-20220061312-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | RHOA, ARHGDIB, ARHGDIA | KDM5A 4068/4885ALDH1A1 3922/4885MAPT 1809/4885 |
| US-11172673-B2 | Platelet storage methods and compositions for same | RHOA, ARHGDIB, ARHGDIA | KDM5A 4068/4885ALDH1A1 3922/4885MAPT 1809/4885 |
| US-20190021307-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | RHOA, ARHGDIB, ARHGDIA | KDM5A 4068/4885ALDH1A1 3922/4885MAPT 1809/4885 |
| US-20040106600-A1 | N-substituted piperidine derivatives as serotonin receptor agents | HTR1A, HTR5A, HTR1B | KDM5A 2286/4885ALDH1A1 515/4885MAPT 2245/4885 |
| US-20040180893-A1 | enzymatically or synthetically prepared alpha-hydroxyglycinamide inhibit the replication of HIV in human serum | ENGASE, GALE, OGA | KDM5A 1137/4885ALDH1A1 1359/4885MAPT 3150/4885 |
| US-20050136406-A1 | Methods of attaching biological compounds to solid supports using triazine | CD2, CD4, MRPS35 | KDM5A 939/4885ALDH1A1 2943/4885MAPT 4540/4885 |
| US-20050192268-A1 | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders | CHRM4, CHRM5, CHRNA10 | KDM5A 1919/4885ALDH1A1 1805/4885MAPT 3110/4885 |
| US-10028503-B2 | Platelet storage methods and compositions for same | RHOA, ARHGDIB, ARHGDIA | KDM5A 4068/4885ALDH1A1 3922/4885MAPT 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.