SCHEMBL13490262

SCHEMBL13490262

O=C(/C=C/c1cccc(C(F)(F)F)c1)OCCNC(=S)NC1CCc2c(F)cccc21

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CCR2 P41597 1/20 0.39
MAPT P10636 2/20 0.39
ALOX5 P09917 1/20 0.39
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PDE10A Q9Y233 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13490205 0.89 AKR1B10 (0.41) MEN1KMT2AALOX5ATMLMNA
SCHEMBL13490277 0.83 HTT (0.49) L3MBTL1HTTPDE10AMAOB
SCHEMBL13490266 0.82 PDE10A (0.41) MEN1KMT2APDE10AMAOB
SCHEMBL13490236 0.82 MAPT (0.44) HTTMEN1KMT2AMAPTLMNA
SCHEMBL13490246 0.79 TAS1R3 (0.40) MEN1KMT2AMAPTPDE10A
SCHEMBL13490201 0.77 KMT2A (0.44) MEN1KMT2AMAPTLMNAPDE10A
SCHEMBL13490245 0.76 PDE10A (0.40) MEN1KMT2APDE10A
SCHEMBL13490267 0.76 PDE10A (0.38) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL13490210 0.76 L3MBTL1 (0.42) L3MBTL1HTTMEN1KMT2AMAPT
SCHEMBL13490214 0.75 SMN1; SMN2 (0.41) MEN1KMT2AMAPTLMNAPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048699-A1 CHEMICAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 US disclosed
US-20100048699-A1 CHEMICAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048699-A1 CHEMICAL COMPOUNDS ACHE, TYR, SGMS1 L3MBTL1 1122/4885HTT 1324/4885MEN1 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.