Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490236 | 0.89 | MAPT (0.44) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13490262 | 0.89 | L3MBTL1 (0.43) | ATMPDE10ALMNAMEN1KMT2A | |
| SCHEMBL14304239 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2PDE10ALMNAMEN1KMT2A | |
| SCHEMBL13490249 | 0.83 | TRPM8 (0.39) | SMN1; SMN2PDE10ALMNAMEN1KMT2A | |
| SCHEMBL13490305 | 0.82 | PDE10A (0.44) | PDE10ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13490250 | 0.82 | PTGIR (0.38) | PDE10AMEN1KMT2AALDH1A1 | |
| SCHEMBL13490211 | 0.81 | TAS1R3 (0.41) | PDE10AMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL13490201 | 0.80 | KMT2A (0.44) | SMN1; SMN2PDE10ALMNAMEN1KMT2A | |
| SCHEMBL13490268 | 0.79 | PDE10A (0.39) | PDE10AMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL13490225 | 0.79 | ALDH1A1 (0.41) | PDE10AMEN1KMT2AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | AKR1B10 2797/4885AKR1B1 2251/4885SMN1; SMN2 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.