Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738426 | 0.83 | XDH (0.35) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19025097 | 0.83 | XDH (0.35) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4013424 | 0.83 | XDH (0.32) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13494172 | 0.81 | ADK (0.30) | — | |
| SCHEMBL4013900 | 0.79 | ALDH1A1 (0.33) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4020234 | 0.79 | ABL1 (0.36) | — | |
| SCHEMBL13494110 | 0.79 | ADK (0.38) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13494103 | 0.78 | ADK (0.34) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16497062 | 0.77 | ADK (0.41) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1737262 | 0.77 | XDH (0.39) | XDHPRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015637-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |