Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494169 | 0.84 | GPR35 (0.40) | KDRALDH1A1HTTUSP2MAOB | |
| SCHEMBL16521953 | 0.78 | RAB9A (0.33) | HTTGPR35NPC1 | |
| SCHEMBL13494166 | 0.77 | GPR35 (0.41) | ALDH1A1MAOBMAOACA12GPR35 | |
| SCHEMBL20246916 | 0.72 | GPR35 (0.32) | ALDH1A1HTTUSP2MAOBNT5E | |
| SCHEMBL13494165 | 0.71 | MAOB (0.58) | ALDH1A1HTTMAOBCA12CA1 | |
| SCHEMBL13494173 | 0.69 | RAB9A (0.50) | ALDH1A1HTTKDM4ENPC1MEN1 | |
| SCHEMBL13099445 | 0.68 | PSMB8 (0.31) | — | |
| SCHEMBL13099441 | 0.68 | PSMB8 (0.32) | — | |
| SCHEMBL14405916 | 0.67 | KDM4E (0.54) | ALDH1A1MAOBMAOACA12CA2 | |
| SCHEMBL13099429 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | CLSPN, CLTC, HACD3 | KDR 1765/4885ALDH1A1 782/4885HTT 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.