SCHEMBL13495342

SCHEMBL13495342

CON1C(=O)Cc2ccc([N+](=O)[O-])cc2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.43
CASP3 P42574 1/20 0.43
CASP4 P49662 1/20 0.43
CASP7 P55210 1/20 0.43
CASP9 P55211 1/20 0.43
CASP6 P55212 1/20 0.43
TDP2 O95551 1/20 0.43
PARP1 P09874 1/20 0.41
PTPRC P08575 1/20 0.41
S100A4 P26447 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
TLR9 Q9NR96 1/20 0.41
ACHE P22303 1/20 0.40
APP P05067 1/20 0.40
MAOB P27338 1/20 0.40
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13495397 0.79 PTPRC (0.53) CASP1CASP3CASP4CASP7CASP9
SCHEMBL13495340 0.78 KMT2A (0.51) CASP1CASP3CASP6PARP1MEN1
SCHEMBL13495345 0.77 KMT2A (0.42) CASP1CASP3CASP6PARP1MEN1
SCHEMBL13495344 0.77 ALDH1A1 (0.62) CASP1CASP3MEN1KMT2AACHE
SCHEMBL13495339 0.72 RNASEH1 (0.56) CASP1CASP3CASP7CASP6MEN1
SCHEMBL8503139 0.72 PTPRC (0.55) CASP1CASP3CASP4CASP7CASP9
SCHEMBL5298639 0.72 CASP1 (0.53) CASP1CASP3CASP4CASP7CASP9
SCHEMBL2616865 0.70 TDP2 (0.52) CASP1CASP3CASP4CASP7CASP9
SCHEMBL15727806 0.70 HTR1A (0.50) CASP1CASP3CASP4CASP7CASP9
SCHEMBL1468627 0.69 NPC1 (0.61) MEN1KMT2ALMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same IGF1R, CCNA1, MYC CASP1 1381/4885CASP3 4288/4885CASP4 4039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.