Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | RORB | Q92753 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013642 | 0.81 | CASP1 (0.47) | KDM4EHSD17B10ALDH1A1CYP1A2DYRK1A | |
| SCHEMBL27863432 | 0.79 | NOTUM (0.48) | KDM4ERORCRORBHSD17B10MEN1 | |
| SCHEMBL3024901 | 0.78 | TDO2 (0.45) | NPC1TSHRRAB9ASMN1; SMN2NOTUM | |
| SCHEMBL9138126 | 0.77 | ADORA2A (0.51) | KDM4ERORCRORBHSD17B10MEN1 | |
| SCHEMBL3970891 | 0.75 | CNR2 (0.53) | KDM4ERORCRORBHSD17B10MEN1 | |
| SCHEMBL11624655 | 0.75 | ADORA2A (0.49) | KDM4ERORCRORBHSD17B10MEN1 | |
| SCHEMBL30041839 | 0.75 | CYP2A6 (0.43) | KDM4EMEN1HPGDKMT2ANPC1 | |
| SCHEMBL527009 | 0.75 | CYP2A6 (0.43) | KDM4EMEN1HPGDKMT2ANPC1 | |
| SCHEMBL12130901 | 0.75 | RAB9A (0.42) | HSD17B10MEN1HPGDKMT2ANPC1 | |
| SCHEMBL8740101 | 0.74 | MAOB (0.52) | KDM4ERORCRORBHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | claimed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | claimed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | claimed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | disclosed |
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| CN-102395593-B | Preparation and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2015-08-12 | — | — | CN | disclosed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215000-A1 | Production And Use Of Zinc Amides | SCLY, CBR3, SCO2 | KDM4E 2931/4885RORC 3342/4885RORB 2491/4885 |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | GLRX3, SCLY, SFXN1 | KDM4E 3350/4885RORC 1862/4885RORB 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.