Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | HPD | P32754 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495669 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1ALDH3A1NR1H2NR1H3 | |
| SCHEMBL13495696 | 0.80 | NR1H2 (0.61) | ALDH3A1NR1H2NR1H3CHEK1ATR | |
| SCHEMBL13495639 | 0.79 | ACSS2 (0.46) | GLAPTGS2ALDH3A1CHEK1ATR | |
| SCHEMBL13495645 | 0.75 | POLB (0.41) | GLAL3MBTL1ALDH3A1NR1H2NR1H3 | |
| SCHEMBL13495638 | 0.74 | PTGS2 (0.47) | PTGS2PTGS1ALDH3A1ACSS2 | |
| SCHEMBL30423958 | 0.73 | CYP11B1 (0.59) | PTGS2PTGS1CYP11B1CYP11B2ACSS2 | |
| SCHEMBL13495634 | 0.72 | POLB (0.44) | PTGS2ALDH3A1CHEK1ATRPDCD1 | |
| SCHEMBL13495644 | 0.72 | HTT (0.48) | PTGS2ALDH3A1NR1H2NR1H3CHEK1 | |
| SCHEMBL13495671 | 0.72 | POLB (0.42) | GLAPTGS2L3MBTL1ALDH3A1CHEK1 | |
| Hydrochloric Acid SCHEMBL29396259 | 0.72 | CYP11B1 (0.57) | PTGS2PTGS1CYP11B1CYP11B2ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |