Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495638 | 0.84 | PTGS2 (0.47) | POLBGSRALDH3A1ACSS2PTGS2 | |
| SCHEMBL13495669 | 0.83 | PTGS2 (0.51) | POLBGSRALDH3A1PTGS2 | |
| SCHEMBL13495644 | 0.80 | HTT (0.48) | POLBGSRALDH3A1PIK3CAMTOR | |
| SCHEMBL13495634 | 0.80 | POLB (0.44) | POLBGSRALDH3A1PIK3CAMTOR | |
| SCHEMBL13495635 | 0.79 | ALDH1A1 (0.43) | POLBGSRALDH3A1MAPK1TSHR | |
| SCHEMBL13495747 | 0.79 | POLB (0.45) | POLBGSRPIK3CAMTORPIK3CD | |
| SCHEMBL13495748 | 0.77 | PIK3CA (0.54) | POLBGSRPIK3CAMTORPIK3CD | |
| SCHEMBL13495645 | 0.75 | POLB (0.41) | POLBGSRALDH3A1PIK3CAPIK3CD | |
| SCHEMBL13495653 | 0.74 | MAPK1 (0.66) | POLBGSRALDH3A1PIK3CAMTOR | |
| SCHEMBL13495641 | 0.74 | HPD (0.47) | POLBGSRPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |