SCHEMBL13502067

SCHEMBL13502067

CC(=O)c1cc2c3cc(C(C)=O)c(C)cc3p(-c3ccccc3)c2cc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 3/20 0.37
▸ AKR1C2 P52895 3/20 0.37
▸ MAPT P10636 4/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ NSD2 O96028 1/20 0.37
▸ MCL1 Q07820 1/20 0.37
▸ MAOB P27338 1/20 0.36
▸ ALDH1A1 P00352 7/20 0.36
▸ HPGD P15428 4/20 0.36
▸ NPC1 O15118 3/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ AKR1B10 O60218 1/20 0.35
▸ AKR1B1 P15121 1/20 0.35
▸ AKR1C4 P17516 1/20 0.35
▸ AKR1C1 Q04828 1/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ CES2 O00748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502070 0.77 HTT (0.47) MAPTKDM4EALDH1A1HPGDRAB9A
SCHEMBL13502071 0.77 GAA (0.41) KMT2AMEN1POLBALDH1A1HPGD
SCHEMBL13502048 0.73 ACHE (0.35) KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL13502049 0.73 CD44 (0.33) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL13502063 0.69 LDHA (0.47) LDHA
SCHEMBL13502060 0.68 — —
SCHEMBL14781353 0.67 KDM4E (0.50) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL4403107 0.67 SMN1; SMN2 (0.52) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL13502079 0.67 CYP1A2 (0.39) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL14215537 0.66 ALOX5 (0.39) KMT2AMEN1ALDH1A1NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
EP-2067807-A1 New polymer and polymer light-emitting device using the same Sumitomo Chemical Company, Limited (JP) 2009-06-10 — — EP disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A AKR1C3 682/4885AKR1C2 1155/4885MAPT 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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