Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806471 | 0.80 | LMNA (0.40) | SMN1; SMN2MAPTKDRMCL1LMNA | |
| SCHEMBL2806467 | 0.80 | LMNA (0.40) | SMN1; SMN2MAPTKDRMCL1LMNA | |
| SCHEMBL14017690 | 0.78 | MCL1 (0.44) | SMN1; SMN2MAPTMCL1LMNAHPGD | |
| Malonic Acid SCHEMBL2415013 | 0.77 | LMNA (0.39) | SMN1; SMN2MAPTKDRMCL1LMNA | |
| SCHEMBL13515708 | 0.76 | MEN1 (0.42) | SMN1; SMN2MAPTLMNAHPGDKDM4E | |
| SCHEMBL12496025 | 0.76 | LMNA (0.37) | SMN1; SMN2MAPTKDRMCL1LMNA | |
| SCHEMBL1576555 | 0.76 | LMNA (0.37) | SMN1; SMN2MAPTKDRMCL1LMNA | |
| SCHEMBL17368887 | 0.72 | HDAC1 (0.46) | SMN1; SMN2MAPTLMNAEGFRKDM4E | |
| SCHEMBL15341665 | 0.72 | NAAA (0.63) | SMN1; SMN2LMNAHPGDALDH1A1KMT2A | |
| SCHEMBL2807525 | 0.71 | KMT2A (0.44) | MAPTMCL1LMNAEGFRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535947-B1 | Diorganosiloxane derivatives containing a 4,4-diarylbutadiene moiety, sunscreen compositions containing them and their uses | OREAL (FR) | 2010-01-06 | — | — | EP | disclosed |