Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798564 | 0.75 | QPCT (0.52) | CYP1A2CYP2C9QPCTKMT2AALDH1A1 | |
| SCHEMBL21923049 | 0.74 | CYP1A2 (0.52) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL17690362 | 0.74 | CYP1A2 (0.52) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL1186988 | 0.74 | ENPP2 (0.56) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL15555209 | 0.74 | CYP1A2 (0.52) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL6518759 | 0.74 | CYP2C9 (0.58) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL12841347 | 0.74 | CYP1A2 (0.52) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL10022377 | 0.73 | NOTUM (0.55) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL7798192 | 0.73 | CYP2C9 (0.47) | MAPTLMNACYP1A2CYP2C9QPCT | |
| SCHEMBL256624 | 0.72 | CYP3A4 (0.52) | MAPTLMNACYP1A2CYP2C9QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050460-B | BN micropowder reinforced phenolic resin for copper-clad plate and preparation method thereof | 江苏耀鸿电子有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117050460-A | BN micropowder reinforced phenolic resin for copper-clad plate and preparation method thereof | 江苏耀鸿电子有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-117050460-B | BN micropowder reinforced phenolic resin for copper-clad plate and preparation method thereof | 江苏耀鸿电子有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117050460-A | BN micropowder reinforced phenolic resin for copper-clad plate and preparation method thereof | 江苏耀鸿电子有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-10428022-B2 | Iminosugars useful for the treatment of viral diseases | EMERGENT VIROLOGY LLC (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2018-10-25 | — | — | US | disclosed |
| US-10000482-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-9802937-B2 | Substituted pyrazolo{4,3-D}pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-10-31 | — | — | US | disclosed |
| US-9637491-B2 | Pyrazolo[4,3-D]pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-05-02 | — | — | US | disclosed |
| US-9579320-B2 | Inhibitors of syk and JAK protein kinases | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-6924302-B2 | Substituted triazole diamine derivatives as kinase inhibitors | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040077699-A1 | Substituted triazole diamine derivatives as kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-04-22 | — | — | US | disclosed |
| EP-1355889-A1 | SUBSTITUTED TRIAZOLE DIAMINE DERIVATIVES AS KINASE INHIBITORS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002057240-A1 | SUBSTITUTED TRIAZOLE DIAMINE DERIVATIVES AS KINASE INHIBITORS | ORTHO MC NEIL PHARMACEUTICAL, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| US-6048878-A | Substituted piperidine derivatives as selective agonists of 5-HT receptors | MERCK SHARP & DOHME LTD. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0581538-B1 | 4-Substituted 1,2,4-triazole derivatives | MERCK SHARP & DOHME (GB) | 1999-03-03 | — | — | EP | disclosed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |
| US-5554629-A | HEADACHES | MERCK, SHARP & DOHME LTD. (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0581538-A1 | 4-Substituted 1,2,4-triazole derivatives | MERCK SHARP & DOHME LTD. (GB) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428022-B2 | Iminosugars useful for the treatment of viral diseases | GBA1, MAN2B1, GBA2 | MAPT 3233/4885LMNA 1538/4885CYP1A2 1798/4885 |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | MAPT 470/4885LMNA 3015/4885CYP1A2 3832/4885 |
| US-20040077699-A1 | Substituted triazole diamine derivatives as kinase inhibitors | MAP2K2, PRKDC, MAP2K3 | MAPT 1570/4885LMNA 3230/4885CYP1A2 4754/4885 |
| US-10000482-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | MAPT 438/4885LMNA 3115/4885CYP1A2 3709/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | MAPT 438/4885LMNA 3115/4885CYP1A2 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.