SCHEMBL5156017

SCHEMBL5156017

NCCCC[C@H](NC(=O)CN)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGDS O60760 1/20 0.48
▸ FOLH1 Q04609 1/20 0.45
▸ SLC15A2 Q16348 1/20 0.44
▸ SLC6A5 Q9Y345 1/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ GSR P00390 1/20 0.39
▸ NMT2 O60551 1/20 0.39
▸ NMT1 P30419 1/20 0.39
▸ SIRT6 Q8N6T7 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39
▸ NOD1 Q9Y239 1/20 0.38
▸ RNPEP Q9H4A4 1/20 0.38
▸ ROCK2 O75116 2/20 0.38
▸ PRKACA P17612 1/20 0.38
▸ AKT3 Q9Y243 1/20 0.38
▸ GHSR Q92847 1/20 0.37
▸ SCN9A Q15858 1/20 0.37
▸ SSTR5 P35346 1/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32675730 1.00 HPGDS (0.48) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL22341404 0.94 HPGDS (0.43) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL13697774 0.90 HPGDS (0.49) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL1352085 0.88 HPGDS (0.43) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL13271590 0.87 SIRT6 (0.44) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL22133062 0.87 HPGDS (0.42) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL15302247 0.87 HPGDS (0.42) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL2159831 0.87 HPGDS (0.42) HPGDSFOLH1SLC15A2SLC6A5TLR2
SCHEMBL24451086 0.86 HPGDS (0.35) HPGDSFOLH1SLC15A2TLR2NOD1
SCHEMBL13363677 0.85 SLC6A5 (0.56) HPGDSFOLH1SLC6A5TLR2NMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319540-B2 HIF 1-alpha antisense oligonucleotides OLIPASS CORPORATION (KR) 2022-05-03 — — US claimed
US-12624068-B2 Exon skipping by peptide nucleic acid derivatives OLIPASS CORPORATION (KR) 2026-05-12 — — US disclosed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 — — EP disclosed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP disclosed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 — — EP disclosed
EP-4251210-B1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S R L (IT) 2025-03-19 — — EP disclosed
EP-4251211-B1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXIC DRUGS ANBITION S R L (IT) 2025-02-26 — — EP disclosed
EP-3603658-B1 PEPTIDE FOR USE IN THE TREATMENT OF HEART FAILURE RESULTING FROM HYPERTROPHIC CARDIOMYOPATHY UNIV CORNELL (US) 2025-01-08 — — EP disclosed
EP-3573645-B1 ALPHA-MSH ANALOGUES USED IN THE TREATMENT OF XERODERMA PIGMENTOSUM VALLAURIX MC S A R L (MC) 2024-03-13 — — EP disclosed
EP-4302829-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2024-01-10 — — EP disclosed
EP-4251211-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS Anbition S.r.l. (IT) 2023-10-04 — — EP disclosed
EP-4251210-A1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS Anbition S.r.l. (IT) 2023-10-04 — — EP disclosed
EP-3513800-B1 AROMATIC-CATIONIC PEPTIDE FOR USE IN THE TREATMENT OF ANTIPHOSPHOLIPID SYNDROME UNIV CORNELL (US) 2022-12-07 — — EP disclosed
US-20220273830-A1 COMPOUNDS AND METHODS OF USE Edinburgh Molecular Imaging Limited (GB) 2022-09-01 — — US disclosed
WO-2022112865-A1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2022-06-02 — — WO disclosed
WO-2022112866-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2022-06-02 — — WO disclosed
US-11319540-B2 HIF 1-alpha antisense oligonucleotides OLIPASS CORPORATION (KR) 2022-05-03 — — US disclosed
US-20220024981-A1 CYCLIC PEPTIDES AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDERS NOVARTIS AG (CH) 2022-01-27 — — US disclosed
EP-1348714-B1 Polypeptide useful as anti-allergic/antiasthmatic, methods for the preparation thereof and pharmaceutical compositions containing such polypeptide and their use COUNCIL SCIENT IND RES (IN) 2007-01-03 — — EP disclosed
EP-1348714-A1 Polypeptide useful as anti-allergic/antiasthmatic, methods for the preparation thereof and pharmaceutical compositions containing such polypeptide and their use COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319540-B2 HIF 1-alpha antisense oligonucleotides HIF1A, HIF1AN, UPF1 HPGDS 377/4885FOLH1 890/4885SLC15A2 1867/4885
US-12624068-B2 Exon skipping by peptide nucleic acid derivatives NSUN2, NSUN3, UPF1 HPGDS 2241/4885FOLH1 1261/4885SLC15A2 1036/4885
US-20220024981-A1 CYCLIC PEPTIDES AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDERS PCSK9, PCSK7, PCSK6 HPGDS 3430/4885FOLH1 1934/4885SLC15A2 1999/4885
US-20220273830-A1 COMPOUNDS AND METHODS OF USE VIP, QPCT, CALCRL HPGDS 1365/4885FOLH1 17/4885SLC15A2 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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