SCHEMBL13525209

SCHEMBL13525209

CNc1ccc(N=C2C=C(C)C(=O)C=C2N)cc1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13525216 0.80 CA12 (0.40) MEN1LMNAGAAMAPK1KMT2A
SCHEMBL24514478 0.76 PABPC1 (0.37) MEN1LMNAGAAMAPK1KMT2A
SCHEMBL24443643 0.76 PABPC1 (0.37) MEN1LMNAGAAMAPK1KMT2A
SCHEMBL10046784 0.74 PABPC1 (0.36) MEN1LMNAGAAMAPK1KMT2A
SCHEMBL11248717 0.71 HTT (0.33) —
SCHEMBL13525217 0.70 HTT (0.33) —
SCHEMBL1435815 0.69 KDM4E (0.33) GAA
SCHEMBL1435819 0.69 KDM4E (0.33) GAA
SCHEMBL24213340 0.68 LMNA (0.34) MEN1LMNAGAAMAPK1KMT2A
SCHEMBL10046785 0.68 CYP3A4 (0.40) MEN1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645304-B2 Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation L'OREAL S.A. (FR) 2010-01-12 — — US disclosed
US-7645304-B2 Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation L'OREAL S.A. (FR) 2010-01-12 — — US disclosed
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation L'OREAL S.A. (FR) 2008-05-29 — — US disclosed
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation L'OREAL S.A. (FR) 2008-05-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation KRT18, IK, KLK5 MEN1 1750/4885LMNA 1287/4885GAA 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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