SCHEMBL24213340

SCHEMBL24213340

CC1=C/C(=N/c2ccc(O)cc2C)C(N)=CC1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.34
▸ GAA P10253 3/20 0.34
▸ POLB P06746 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ THRB P10828 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ PLK1 P53350 1/20 0.33
▸ PLK2 Q9NYY3 1/20 0.33
▸ SIGMAR1 Q99720 1/20 0.32
▸ ALOX12 P18054 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ GPR55 Q9Y2T6 1/20 0.31
▸ ESR1 P03372 1/20 0.31
▸ ESR2 Q92731 1/20 0.31
▸ GLO1 Q04760 2/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10046784 0.80 PABPC1 (0.36) LMNAGAAMAPTALDH1A1MEN1
SCHEMBL13525219 0.79 CYP3A4 (0.35) MAPTALDH1A1MEN1KMT2APLK1
SCHEMBL15315666 0.78 SIGMAR1 (0.40) LMNAGAAMAPTALDH1A1MEN1
SCHEMBL11405838 0.74 LMNA (0.33) LMNAGAAPOLBMAPTALDH1A1
SCHEMBL11714307 0.72 MAPT (0.37) LMNAGAAPOLBMAPTALDH1A1
SCHEMBL11414969 0.70 MAPT (0.36) LMNAGAAPOLBMAPTALDH1A1
SCHEMBL11315992 0.70 CA12 (0.33) LMNAPOLBMEN1KMT2AESR1
SCHEMBL24443643 0.70 PABPC1 (0.37) LMNAGAAPOLBMAPTALDH1A1
SCHEMBL24514478 0.70 PABPC1 (0.37) LMNAGAAPOLBMAPTALDH1A1
SCHEMBL13525228 0.70 ALDH1A1 (0.37) LMNAGAAMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11344489-B2 Azomethine dye chromophores BASF SE (DE) 2022-05-31 — — US disclosed
US-20220016007-A1 Azomethine Dye Chromophores BASF SE (DE) 2022-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11344489-B2 Azomethine dye chromophores KRT18, IK, JUP LMNA 333/4885GAA 4614/4885POLB 692/4885
US-20220016007-A1 Azomethine Dye Chromophores KRT18, IK, JUP LMNA 333/4885GAA 4614/4885POLB 692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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