SCHEMBL24514478

SCHEMBL24514478

CC1=C/C(=N\c2ccc(N)cc2)C(N)=CC1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PABPC1 P11940 1/20 0.37
▸ MAPT P10636 6/20 0.34
▸ RAB9A P51151 5/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ NPC1 O15118 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ LMNA P02545 3/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ GAA P10253 2/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ PLK1 P53350 2/20 0.32
▸ PLK2 Q9NYY3 2/20 0.32
▸ NOS3 P29474 1/20 0.32
▸ NOS1 P29475 1/20 0.32
▸ NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24443643 1.00 PABPC1 (0.37) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL13525199 0.88 PABPC1 (0.41) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL10046784 0.87 PABPC1 (0.36) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL13525216 0.84 CA12 (0.40) PABPC1MEN1KMT2ALMNAMAPK1
SCHEMBL22699857 0.79 MAPT (0.34) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL10782928 0.79 PABPC1 (0.41) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL6125203 0.79 MAPT (0.48) MAPTRAB9AMEN1KMT2ANPC1
SCHEMBL13525209 0.76 MEN1 (0.31) MEN1KMT2ALMNAMAPK1GAA
SCHEMBL13525222 0.75 PABPC1 (0.36) PABPC1MAPTRAB9AMEN1KMT2A
SCHEMBL15039505 0.74 DNM1 (0.41) MAPTRAB9AMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346669-A1 PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM L'OREAL (FR) 2023-11-02 — — US disclosed
US-20230346669-A1 PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM L'OREAL (FR) 2023-11-02 — — US disclosed
US-20230310294-A1 COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION L'OREAL (FR) 2023-10-05 — — US disclosed
US-20230310294-A1 COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION L'OREAL (FR) 2023-10-05 — — US disclosed
US-11672747-B2 Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same L'OREAL (FR) 2023-06-13 — — US disclosed
US-11672747-B2 Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same L'OREAL (FR) 2023-06-13 — — US disclosed
US-20220183944-A1 PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2022-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346669-A1 PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM KRT18, DSG1, KRTCAP2 PABPC1 2806/4885MAPT 355/4885RAB9A 3248/4885
US-20230310294-A1 COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION KRT18, KAT2B, SPIN2B PABPC1 3926/4885MAPT 1259/4885RAB9A 1928/4885
US-11672747-B2 Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same KRT18, MARK1, IK PABPC1 2101/4885MAPT 465/4885RAB9A 3926/4885
US-20220183944-A1 PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME KRT18, MARK1, IK PABPC1 2101/4885MAPT 465/4885RAB9A 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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