SCHEMBL13532042

SCHEMBL13532042

COC1=C(NCC(=O)O)CC(O)(CO)C/C1=N\C(C(=O)O)C(C)O

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 2/20 0.59
▸ NFE2L2 Q16236 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19129823 1.00 KEAP1 (0.59) KEAP1NFE2L2
SCHEMBL19130207 0.93 KEAP1 (0.55) KEAP1NFE2L2
SCHEMBL19146576 0.89 KEAP1 (0.56) KEAP1NFE2L2
SCHEMBL24473720 0.88 KEAP1 (0.60) KEAP1NFE2L2
SCHEMBL24473722 0.88 KEAP1 (0.54) KEAP1NFE2L2
SCHEMBL19129847 0.88 KEAP1 (0.54) KEAP1NFE2L2
SCHEMBL24473698 0.87 KEAP1 (0.54) KEAP1NFE2L2
SCHEMBL19129822 0.85 KEAP1 (0.55) KEAP1NFE2L2
SCHEMBL13532040 0.85 KEAP1 (0.55) KEAP1NFE2L2
SCHEMBL30892082 0.85 KEAP1 (0.55) KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168253-A1 PRODUCTION PROMOTER OF TYPE I COLLAGEN OR ELASTIN DR'S CHOICE CO., LTD. (JP) 2022-06-02 — — US disclosed
US-9522167-B2 Alphanizomenon flos aquae preparation, extracts and purified components thereof for the treatment of neurological, neurodegenerative and mood disorders Nutratec, s.r.l. (IT) 2016-12-20 — — US disclosed
US-9522167-B2 Alphanizomenon flos aquae preparation, extracts and purified components thereof for the treatment of neurological, neurodegenerative and mood disorders Nutratec, s.r.l. (IT) 2016-12-20 — — US disclosed
US-8337858-B2 Extracts of Aphanizomenon Flos Aquae and nutritional, cosmetic and pharmaceutical compositions containing the same NUTRATEC S.R.L. (IT) 2012-12-25 — — US disclosed
US-8337858-B2 Extracts of Aphanizomenon Flos Aquae and nutritional, cosmetic and pharmaceutical compositions containing the same NUTRATEC S.R.L. (IT) 2012-12-25 — — US disclosed
US-20100021493-A1 EXTRACTS OF APHANIZOMENON FLOS AQUAE AND NUTRITIONAL, COSMETIC AND PHARMACEUTICAL COMPOSITONS CONTAINING THE SAME NUTRATEC S.R.L. (IT) 2010-01-28 — — US disclosed
US-20100021493-A1 EXTRACTS OF APHANIZOMENON FLOS AQUAE AND NUTRITIONAL, COSMETIC AND PHARMACEUTICAL COMPOSITONS CONTAINING THE SAME NUTRATEC S.R.L. (IT) 2010-01-28 — — US disclosed
US-20090311286-A1 Alphanizomenon Flos Aquae Preparation, Extracts and Purified Components Thereof for the Treatment of Neurological, Neurodegenerative and Mood Disorders NUTRATEC S.R.L. (IT) 2009-12-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090311286-A1 Alphanizomenon Flos Aquae Preparation, Extracts and Purified Components Thereof for the Treatment of Neurological, Neurodegenerative and Mood Disorders TUBA1A, FECH, NDUFA6 KEAP1 371/4885NFE2L2 1356/4885
US-20220168253-A1 PRODUCTION PROMOTER OF TYPE I COLLAGEN OR ELASTIN COL14A1, COL2A1, COL1A1 KEAP1 746/4885NFE2L2 2052/4885
US-20100021493-A1 EXTRACTS OF APHANIZOMENON FLOS AQUAE AND NUTRITIONAL, COSMETIC AND PHARMACEUTICAL COMPOSITONS CONTAINING THE SAME CUTA, AAAS, FAH KEAP1 658/4885NFE2L2 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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