Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353889 | 0.81 | HRH4 (0.49) | HTR7HRH4ALDH1A1HPGDMAPT | |
| SCHEMBL13139566 | 0.80 | HTR7 (0.53) | HTR7ALDH1A1HPGDKRASSMN1; SMN2 | |
| SCHEMBL13537353 | 0.79 | PTGS2 (0.40) | HTR7ALDH1A1HPGDMAPTPOLB | |
| SCHEMBL3356709 | 0.79 | HTR7 (0.79) | HTR7ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2870320 | 0.79 | KMT2A (0.54) | HTR7L3MBTL1KRASPOLBKMT2A | |
| SCHEMBL2873839 | 0.79 | KMT2A (0.54) | HTR7L3MBTL1KRASPOLBKMT2A | |
| SCHEMBL12605568 | 0.77 | KMT2A (0.56) | ALDH1A1L3MBTL1SMN1; SMN2MAPTPOLB | |
| SCHEMBL3356235 | 0.77 | HTR7 (0.50) | HTR7ALDH1A1KRASMAPTKMT2A | |
| SCHEMBL3357957 | 0.77 | HTR7 (0.63) | HTR7HRH4ALDH1A1 | |
| SCHEMBL3356633 | 0.77 | HTR7 (0.50) | HTR7ALDH1A1L3MBTL1KRASMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |