Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 7/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537353 | 0.82 | PTGS2 (0.40) | KMT2APTGS2HTR7MEN1USP2 | |
| SCHEMBL12605568 | 0.81 | KMT2A (0.56) | KMT2APTGS2CXCR3ALDH1A1HSD17B10 | |
| SCHEMBL3356853 | 0.81 | HTR7 (0.62) | HRH4KMT2AHTR7MEN1ALDH1A1 | |
| SCHEMBL13139567 | 0.78 | NTSR1 (0.45) | KMT2AUSP2ALDH1A1HPGDTSHR | |
| SCHEMBL2869168 | 0.76 | KMT2A (0.60) | KMT2AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL3353214 | 0.76 | LMNA (0.44) | KMT2AUSP2ALDH1A1HPGDTSHR | |
| SCHEMBL3351880 | 0.75 | HTR7 (0.55) | HTR7 | |
| SCHEMBL3354522 | 0.74 | GRIN2B (0.45) | NTSR1 | |
| SCHEMBL3354646 | 0.74 | NTSR1 (0.51) | KMT2AUSP2ALDH1A1HPGDTSHR | |
| SCHEMBL3355234 | 0.74 | KDM4E (0.48) | KMT2AMEN1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |