Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539264 | 0.84 | SMN1; SMN2 (0.50) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL69492 | 0.82 | MEN1 (0.58) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1221862 | 0.81 | MEN1 (0.57) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5935124 | 0.79 | RAB9A (0.52) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12882360 | 0.79 | RAB9A (0.52) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12906820 | 0.79 | RAB9A (0.52) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24198729 | 0.75 | RET (0.48) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1221564 | 0.75 | MEN1 (0.61) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25415567 | 0.75 | RET (0.56) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1082911 | 0.75 | RAB9A (0.47) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016313-A1 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016313-A1 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | ALPI, SI, FABP2 | RAB9A 1635/4885POLB 1508/4885NPC1 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.