Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12882360 | 0.81 | RAB9A (0.52) | RETGSK3BRAB9ANPC1ALPL | |
| SCHEMBL69492 | 0.81 | MEN1 (0.58) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL1221564 | 0.81 | MEN1 (0.61) | RETRAB9ANPC1ALPLALPI | |
| SCHEMBL69243 | 0.80 | RAB9A (0.50) | RETRAB9ANPC1ALPLALPI | |
| Hydrochloric Acid SCHEMBL1221862 | 0.80 | MEN1 (0.57) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL17511039 | 0.79 | RAB9A (0.49) | RETRAB9ANPC1ALPLALPI | |
| SCHEMBL17883357 | 0.79 | ITK (0.53) | RAB9ANPC1LMNAMEN1PKM | |
| SCHEMBL5935124 | 0.78 | RAB9A (0.52) | RETRAB9ANPC1ALPLALPI | |
| SCHEMBL12906820 | 0.78 | RAB9A (0.52) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL17511067 | 0.78 | RAB9A (0.48) | RETCHEK1PIM1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365927-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2023-11-16 | — | — | US | claimed |
| EP-4230731-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | Institute Of Zoology, Chinese Academy Of Sciences (CN) | 2023-08-23 | — | — | EP | claimed |
| WO-2022077549-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | 中国科学院动物研究所 | 2022-04-21 | — | — | WO | claimed |
| CN-114369572-A | Composition and method for transdifferentiating non-neuronal cells into neurons | 中国科学院动物研究所 | 2022-04-19 | — | — | CN | claimed |
| US-20230365927-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4230731-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | Institute Of Zoology, Chinese Academy Of Sciences (CN) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022077549-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | 中国科学院动物研究所 | 2022-04-21 | — | — | WO | disclosed |
| CN-114369572-A | Composition and method for transdifferentiating non-neuronal cells into neurons | 中国科学院动物研究所 | 2022-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365927-A1 | COMPOSITION AND METHOD FOR TRANSDIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS | MYO1B, MYH14, MYO3A | RET 3794/4885CHEK1 3615/4885PDGFRB 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.