Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69492 | 0.85 | MEN1 (0.58) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1221862 | 0.84 | MEN1 (0.57) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12882360 | 0.82 | RAB9A (0.52) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12906820 | 0.82 | RAB9A (0.52) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13539265 | 0.79 | RAB9A (0.49) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25415567 | 0.78 | RET (0.56) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24198729 | 0.78 | RET (0.48) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1221564 | 0.78 | MEN1 (0.61) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL69842 | 0.74 | KMT2A (0.64) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1082911 | 0.74 | RAB9A (0.47) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258729-A1 | Antibacterial pyrazole carboxylic acid hydrazides | MICROBIOTIX, INC. | 2006-11-16 | — | — | US | disclosed |
| EP-1549143-A2 | ANTIBACTERIAL PYRAZOLE CARBOXYLIC ACID HYDRAZIDES | Microbiotix, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004094370-A2 | ANTIBACTERIAL PYRAZOLE CARBOXYLIC ACID HYDRAZIDES | MICROBIOTIX, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258729-A1 | Antibacterial pyrazole carboxylic acid hydrazides | POLR2H, POLRMT, POLR2E | RAB9A 2248/4885POLB 5/4885NPC1 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.