Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906611 | 0.91 | HRH1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL13540691 | 0.72 | ALDH1A1 (0.47) | ALDH1A1SIGMAR1 | |
| SCHEMBL4712429 | 0.71 | KMT2A (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL9906714 | 0.67 | SLC2A1 (0.39) | ALDH1A1KMT2ASMN1; SMN2POLBKCNH2 | |
| SCHEMBL9906610 | 0.64 | DRD2 (0.46) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11638310 | 0.63 | HTT (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11635578 | 0.62 | L3MBTL1 (0.69) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2056342 | 0.62 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL5148167 | 0.60 | HRH3 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL28369135 | 0.60 | HTT (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652039-B2 | Such as 1-(2-((3-(4-chlorophenoxy)benzyl)amino)-3-phenyl-propyl)piperidin-4-ol for treatment of tuberculosis; solid phase synthesis | SEQUELLA, INC. (US) | 2010-01-26 | — | — | US | disclosed |