Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Glyceryl Monooleate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.64 |
| ▸ | DGKA | P23743 | 1/20 | 0.77 |
| ▸ | FAAH | O00519 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.57 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyceryl Monooleate SCHEMBL28153678 | 1.00 | DGKA (0.77) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Glyceryl Monooleate SCHEMBL135422 | 1.00 | DGKA (0.77) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Citric Acid SCHEMBL31537560 | 1.00 | DGKA (0.77) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Glyceryl Monooleate SCHEMBL23753213 | 0.98 | DGKA (0.74) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Glyceryl Monolinoleate SCHEMBL3890453 | 0.97 | FAAH (0.73) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Glyceryl Monooleate SCHEMBL23753212 | 0.95 | DGKA (0.69) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Oleic Acid SCHEMBL3743132 | 0.93 | DGKA (0.67) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Oleic Acid SCHEMBL23039169 | 0.93 | DGKA (0.67) | DGKAFAAHKDM4EDUSP3MEN1 | |
| SCHEMBL9972494 | 0.93 | DGKA (0.66) | DGKAFAAHKDM4EDUSP3MEN1 | |
| Glyceryl Monostearate SCHEMBL6652800 | 0.93 | KDM4E (0.74) | DGKAFAAHKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576018-B2 | Active agents for skin and hair care with sensory modifying properties | SYMRISE AG (DE) | 2026-03-17 | — | — | US | claimed |
| US-20260060918-A1 | HIGH-PERMEABILITY INCLUSION FOR SOOTHING SKIN REDNESS, HEAT, AND PAIN, AND PREPARATION METHOD AND USE THEREOF | N.O.D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO.,LTD. (CN) | 2026-03-05 | — | — | US | claimed |
| WO-2025243057-A1 | ANTIMICROBIAL COMPOSITION | Infection Prevention Control Limited (GB) | 2025-11-27 | — | — | WO | claimed |
| US-12350357-B2 | Active agents for skin and hair care with physicochemical modifying properties | SYMRISE AG (DE) | 2025-07-08 | — | — | US | claimed |
| WO-2025102128-A1 | CONCENTRATED COSMETIC COMPOSITION, DILUTED COSMETIC COMPOSITION, USE OF AND METHOD FOR PREPARING A DILUTED COSMETIC COMPOSITION | Natura Cosméticos S.A. (BR) | 2025-05-22 | — | — | WO | claimed |
| CN-119404853-A | Mosquito-repellent composition, mosquito-repellent emulsion and preparation method thereof | 上海丽泓生物科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| WO-2024250789-A1 | HIGH-PERMEABILITY INCLUSION FOR RELIEVING SKIN REDNESS, HEAT AND PAIN, PREPARATION METHOD THEREFOR AND USE THEREOF | 诺德溯源(广州)生物科技有限公司 | 2024-12-12 | — | — | WO | claimed |
| CN-118873463-A | Transparent sun-screening agent and preparation method and application thereof | 广东博然堂生物科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118697653-A | Low-emulsified particle size sun-screening composition capable of realizing sun-screening synergy and preparation method thereof | 中山中研化妆品有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-113507917-B | Skin and hair care actives with physicochemical modification properties | 西姆莱斯有限公司 | 2024-09-03 | — | — | CN | claimed |
| EP-2726185-A1 | MICROEMULSION OF QUATERNARY POLYSILOXANES CONTAINING AMMONIUM GROUPS, PRODUCTION AND USE THEREOF | Evonik Degussa GmbH (DE) | 2014-05-07 | — | — | EP | claimed |
| CN-103648629-A | Microemulsion of quaternary polysiloxanes containing ammonium groups, production and use thereof | EVONIK GOLDSCHMIDT GMBH | 2014-03-19 | — | — | CN | claimed |
| CN-103565693-A | Skin-nourishing and protecting emulsion and preparation method thereof | WANNAN MEDICAL COLLEGE | 2014-02-12 | — | — | CN | claimed |
| US-20130039866-A1 | COMPOSITION FOR THE PROPHYLAXIS OF CANDIDIASIS | Obshchestvo S Ogranichennoj Otvetstvennostyu "WDS" (RU) | 2013-02-14 | — | — | US | claimed |
| EP-2545899-A1 | COMPOSITION FOR THE PROPHYLAXIS OF CANDIDIASIS | Obshchestvo S Ogranichennoj Otvetstvennost'yu "WDS" (RU) | 2013-01-16 | — | — | EP | claimed |
| WO-2013000592-A1 | MICROEMULSION OF QUATERNARY POLYSILOXANES CONTAINING AMMONIUM GROUPS, PRODUCTION AND USE THEREOF | EVONIK GOLDSCHMIDT GMBH (DE) | 2013-01-03 | — | — | WO | claimed |
| EP-2317969-A1 | HAIR TREATMENT MEANS | Henkel AG & Co. KGaA (DE) | 2011-05-11 | — | — | EP | claimed |
| US-7731982-B2 | O/W emulsifier, O/W emulsion and applications thereof | SYMRISE GMBH & CO. KG (US) | 2010-06-08 | — | — | US | claimed |
| WO-2010026009-A1 | HAIR TREATMENT MEANS | HENKEL AG & CO. KGAA (DE) | 2010-03-11 | — | — | WO | claimed |
| US-20060165738-A1 | O/w emulsifier, o/w emulsion and applications thereof | SYMRISE AG (DE) | 2006-07-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060918-A1 | HIGH-PERMEABILITY INCLUSION FOR SOOTHING SKIN REDNESS, HEAT, AND PAIN, AND PREPARATION METHOD AND USE THEREOF | CETP, CUTA, LIPA | MEN1 4692/4885DGKA 614/4885FAAH 1557/4885 |
| US-12576018-B2 | Active agents for skin and hair care with sensory modifying properties | SCD5, SMURF1, SGMS1 | MEN1 4806/4885DGKA 76/4885FAAH 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.