Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543501 | 0.86 | POLB (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGPOLB | |
| SCHEMBL13543309 | 0.85 | MAPT (0.43) | TDP1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13543283 | 0.80 | GSTO1 (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGPOLB | |
| SCHEMBL13543285 | 0.80 | GSTO1 (0.62) | POLBL3MBTL1ALDH1A1KDM4EF10 | |
| SCHEMBL13542961 | 0.78 | IDH2 (0.47) | ALDH1A1MAPTKMT2ATSHRIDH2 | |
| SCHEMBL13542942 | 0.75 | ATM (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGPOLB | |
| SCHEMBL5504049 | 0.72 | CA1 (0.48) | POLBL3MBTL1TDP1HSD17B10KDM4E | |
| SCHEMBL13543287 | 0.72 | SMN1; SMN2 (0.51) | POLBL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13543493 | 0.71 | PTK2B (0.58) | POLBL3MBTL1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL13544674 | 0.71 | ATM (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |