Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614270 | 0.82 | PRSS12 (0.44) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL3622343 | 0.74 | TSHR (0.63) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24489089 | 0.74 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL29694087 | 0.74 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL12040651 | 0.74 | POLB (0.44) | SMN1; SMN2ALDH1A1HPGDPRSS12MAPT | |
| SCHEMBL9283635 | 0.73 | NPC1 (0.63) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL8236138 | 0.72 | F10 (0.55) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL3613996 | 0.71 | F10 (0.51) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL3604203 | 0.71 | PRSS12 (0.47) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A | |
| SCHEMBL3613707 | 0.70 | PRSS12 (0.43) | SMN1; SMN2ALDH1A1HPGDPRSS12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | BAYER HEALTHCARE AG (DE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | PPOX, XDH, PNPO | SMN1; SMN2 1729/4885ALDH1A1 906/4885HPGD 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.