Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15194036 | 0.82 | RXRA (0.49) | MGLLRXRARXRBRXRG | |
| SCHEMBL29955074 | 0.82 | RXRA (0.49) | MGLLRXRARXRBRXRG | |
| SCHEMBL29952370 | 0.80 | MGLL (0.40) | MGLLRXRARXRBRXRG | |
| SCHEMBL13554249 | 0.78 | ENPP2 (0.31) | — | |
| SCHEMBL22828 | 0.77 | ENPP2 (0.42) | MGLL | |
| SCHEMBL29830169 | 0.77 | ENPP2 (0.42) | MGLL | |
| SCHEMBL13554240 | 0.74 | RXRA (0.35) | MGLLRXRARXRBRXRG | |
| SCHEMBL3113375 | 0.73 | RXRA (0.50) | MGLLRXRARXRBRXRG | |
| SCHEMBL29955864 | 0.73 | RXRA (0.50) | MGLLRXRARXRBRXRG | |
| SCHEMBL850950 | 0.73 | MGLL (0.39) | MGLLRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | WNK3, REN, SGK3 | MGLL 4716/4885RXRA 2610/4885RXRB 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.