Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774081 | 0.83 | NPC1 (0.44) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL822806 | 0.80 | EPHX1 (0.42) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL2773946 | 0.78 | CA12 (0.41) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL4298143 | 0.77 | POLB (0.51) | TSHRALDH1A1TDP1KMT2ANPC1 | |
| SCHEMBL10633427 | 0.76 | TRPA1 (0.39) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL27780014 | 0.74 | CES1 (0.52) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL27892938 | 0.72 | CES1 (0.42) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL1271166 | 0.71 | CES1 (0.50) | TSHRALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL9434643 | 0.71 | PAM (0.50) | TSHRALDH1A1TDP1CES1CES2 | |
| SCHEMBL13377791 | 0.71 | EPHX1 (0.41) | TSHRALDH1A1HSD17B10TDP1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166048-B | Method for preparing S- (-) -benzoyl mercapto-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-113166048-B | Method for preparing S- (-) -benzoyl mercapto-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113166048-B | Method for preparing S- (-) -benzoyl mercapto-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113166048-B | Method for preparing S- (-) -benzoyl mercapto-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-3912970-A4 | METHOD FOR PREPARING S-(-)-BENZOYLMERCAPTO-2-METHYLPROPANOIC ACID COMPOUND | Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| CN-113166048-A | Method for preparing S- (-) -benzoyl sulfydryl-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113166048-A | Method for preparing S- (-) -benzoyl sulfydryl-2-methylpropanoic acid compound | 浙江华海药业股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |
| EP-2389360-A2 | A PROCESS FOR THE PREPARATION OF ZOFENOPRIL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Glenmark Generics Limited (IN) | 2011-11-30 | — | — | EP | disclosed |
| US-20110281928-A1 | Process for the preparation of zofenopril and its pharmaceutically acceptable salts thereof | GLENMARK GENERICS LTD (IN) | 2011-11-17 | — | — | US | disclosed |
| US-20110253651-A1 | Drying rack with wrap-around cover | BEHJAT MOHAMMAD KAZEM | 2011-10-20 | — | — | US | disclosed |
| WO-2010084515-A2 | A PROCESS FOR THE PREPARATION OF ZOFENOPRIL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | GLENMARK GENERICS LIMITED (IN) | 2010-07-29 | — | — | WO | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-4559178-A | Resolution of 3-benzoylthio-2-methyl-propanoic acid with (+)-dehydroabietylamine | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0008831-B1 | PROCESS FOR THE PREPARATION OF 1-(3-MERCAPTO-2-D-METHYL-PROPIONYL)-L-PROLINE AND DERIVATIVES THEREOF | Océ-Andeno B.V. (NL) | 1982-03-17 | — | — | EP | disclosed |
| EP-0008833-A1 | Optically active derivatives of mercaptoisobutyric acid and a process for preparing them | Océ-Andeno B.V. (NL) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281928-A1 | Process for the preparation of zofenopril and its pharmaceutically acceptable salts thereof | ACE, REN, PEPD | TSHR 4797/4885ALDH1A1 963/4885HSD17B10 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.