Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773946 | 0.94 | CA12 (0.41) | NPC1RAB9ACES1TSHRCES2 | |
| SCHEMBL2768683 | 0.83 | CES2 (0.42) | NPC1RAB9ACES1CES2ALDH1A1 | |
| SCHEMBL1356205 | 0.83 | TSHR (0.41) | NPC1RAB9ACES1TSHRCES2 | |
| SCHEMBL10499364 | 0.80 | ESR1 (0.46) | TSHRCES2HSD17B10CYP3A4MAPT | |
| SCHEMBL27780014 | 0.77 | CES1 (0.52) | NPC1RAB9ACES1TSHRCES2 | |
| SCHEMBL28764415 | 0.77 | CES2 (0.55) | NPC1RAB9ACES1CES2ALDH1A1 | |
| SCHEMBL27892938 | 0.76 | CES1 (0.42) | CES1TSHRCES2ALDH1A1DAO | |
| SCHEMBL7826990 | 0.74 | KMT2A (0.57) | NPC1RAB9ACES1ALDH1A1TDP1 | |
| SCHEMBL812709 | 0.73 | KMT2A (0.56) | RAB9ACES1TSHRCES2ALDH1A1 | |
| SCHEMBL236901 | 0.73 | ALDH1A1 (0.41) | NPC1RAB9ACES1TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-7714075-B1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-05-11 | — | — | US | disclosed |
| US-7666962-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-23 | — | — | US | disclosed |
| US-7662986-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-16 | — | — | US | disclosed |
| CN-100473646-C | Polymerization with living characteristics | COMMW SCIENT IND RES ORG (AU) | 2009-04-01 | — | — | CN | disclosed |
| US-20080139836-A1 | Polymerization with living characteristics | LE TAM PHUONG | 2008-06-12 | — | — | US | disclosed |
| US-20080139764-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-12 | — | — | US | disclosed |
| CN-1331851-C | Chain transfer agent | DU PONT (US) | 2007-08-15 | — | — | CN | disclosed |
| US-7250479-B2 | Polymerization with living characteristics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
| CN-1673216-A | Chain transfer agent | DU PONT (US) | 2005-09-28 | — | — | CN | disclosed |
| US-20040171777-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-09-02 | — | — | US | disclosed |
| CN-1500813-A | Polymerization with living characteristics | ��Ļ���Ű˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1137144-C | Polymerization with living characteristics | ��Ļ���Ű˾ | 2004-02-04 | — | — | CN | disclosed |
| EP-0910587-B1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | DU PONT (US) | 2001-12-12 | — | — | EP | disclosed |
| CN-1228787-A | Polymerization with living characteristics | DU PONT (US) | 1999-09-15 | — | — | CN | disclosed |
| EP-0910587-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998001478-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139836-A1 | Polymerization with living characteristics | UQCRB, MTR, UQCRC2 | NPC1 4727/4885RAB9A 4194/4885CES1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.