Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420698 | 0.79 | GPR6 (0.37) | SCARB1GPR6 | |
| SCHEMBL1178260 | 0.76 | GPR6 (0.35) | SCARB1RORCGPR6 | |
| SCHEMBL1178262 | 0.76 | GPR6 (0.35) | SCARB1RORCGPR6 | |
| SCHEMBL14217953 | 0.76 | SCARB1 (0.49) | SCARB1HTR6RORCHRH1CA1 | |
| SCHEMBL13563337 | 0.75 | SCARB1 (0.49) | SCARB1HTR6RORCHRH1CA1 | |
| SCHEMBL541977 | 0.75 | RORC (0.59) | SCARB1HTR6RORCHRH1CA1 | |
| SCHEMBL14218042 | 0.71 | HRH1 (0.60) | SCARB1HTR6RORCHRH1CA1 | |
| SCHEMBL13563336 | 0.69 | HTR6 (0.46) | HTR6FABP3FABP4CA1CA2 | |
| SCHEMBL13478810 | 0.69 | HTR6 (0.60) | SCARB1HTR6RORCHRH1CA1 | |
| SCHEMBL13563274 | 0.68 | HTR6 (0.57) | HTR6FABP4CA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297100-B1 | TETRAHYDROCYCLOPENTA[B]INDOLE ANDROGEN RECEPTOR MODULATORS | LILLY CO ELI (US) | 2012-10-31 | — | — | EP | disclosed |