Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355544 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6398255 | 0.82 | AOC3 (0.50) | ALDH1A1CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6493018 | 0.76 | AOC3 (0.51) | CPN1CPB2CYP1A2CYP2D6AOC3 | |
| SCHEMBL6493022 | 0.75 | AOC3 (0.51) | CPN1CPB2AOC3OPRM1MEN1 | |
| SCHEMBL19723310 | 0.73 | AOC3 (0.49) | ALDH1A1CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL11206337 | 0.72 | KDM4E (0.45) | ALDH1A1CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL2238144 | 0.70 | CPN1 (0.49) | CPN1CPB2ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL4609249 | 0.70 | PNMT (0.59) | CPN1CPB2ALDH1A1CYP3A4TSHR | |
| SCHEMBL7146456 | 0.70 | PNMT (0.59) | CPN1CPB2ALDH1A1CYP3A4TSHR | |
| SCHEMBL9152377 | 0.70 | CPN1 (0.49) | CPN1CPB2ALDH1A1CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281821-A9 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100249067-A1 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249067-A1 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | CPN1 3126/4885CPB2 3961/4885ALDH1A1 4063/4885 |
| US-20110281821-A9 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | CPN1 3126/4885CPB2 3961/4885ALDH1A1 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.