SCHEMBL1356441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1356620	0.81	CNR2 (0.44)	MAPTSMN1; SMN2ALDH1A1LMNACNR1
	SCHEMBL1356743	0.81	ABL1 (0.65)	MAPTABL1ALDH1A1CACNA1GCACNA1H
	SCHEMBL8473697	0.78	ABL1 (0.53)	MAPTSMN1; SMN2ABL1ALDH1A1CACNA1G
	SCHEMBL1356745	0.78	KDM4E (0.44)	SIGMAR1LMNAKDM4EHTT
	SCHEMBL1356512	0.77	SIGMAR1 (0.66)	NPC1RAB9AALDH1A1SIGMAR1LMNA
	SCHEMBL1357071	0.76	SIGMAR1 (0.68)	NPC1RAB9AMAPTALDH1A1SIGMAR1
	SCHEMBL1356504	0.75	SIGMAR1 (0.54)	MAPTSMN1; SMN2ALDH1A1SIGMAR1LMNA
	SCHEMBL1356424	0.75	POLB (0.50)	MAPTSMN1; SMN2ALDH1A1SIGMAR1LMNA
	SCHEMBL4655475	0.72	SIGMAR1 (0.56)	NPC1RAB9ASMN1; SMN2ALDH1A1SIGMAR1
	SCHEMBL4655438	0.70	SIGMAR1 (0.51)	MAPTALDH1A1SIGMAR1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.