Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356743 | 0.90 | ABL1 (0.65) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL1356441 | 0.78 | NPC1 (0.43) | ABL1SIGMAR1MAPTKDM4EALDH1A1 | |
| SCHEMBL1356872 | 0.77 | ABL1 (0.60) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL24685633 | 0.73 | ABL1 (0.66) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL1357656 | 0.73 | ABL1 (0.73) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL1356884 | 0.72 | SIGMAR1 (0.63) | ABL1SIGMAR1MAPTKDM4EALDH1A1 | |
| SCHEMBL1357515 | 0.72 | ABL1 (0.58) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL1356919 | 0.71 | SIGMAR1 (0.52) | ABL1SIGMAR1MAPTALDH1A1L3MBTL1 | |
| Oxalic Acid SCHEMBL1356980 | 0.70 | ABL1 (0.56) | ABL1SIGMAR1MAPTELOVL1KDM4E | |
| SCHEMBL1356838 | 0.67 | SIGMAR1 (1.00) | ABL1SIGMAR1ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829867-A1 | Imidazole compounds having pharmaceutical activity towards the sigma receptor | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-09-05 | — | — | EP | disclosed |