SCHEMBL1356872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24685633	0.88	ABL1 (0.66)	ABL1SIGMAR1KDM4EMAPTNOTUM
	SCHEMBL1356743	0.87	ABL1 (0.65)	ABL1SIGMAR1KDM4EMAPTNOTUM
	SCHEMBL4655517	0.84	SIGMAR1 (0.58)	ABL1SIGMAR1KDM4EKCNH2
	SCHEMBL25736178	0.83	ABL1 (0.62)	ABL1SIGMAR1KDM4EMAPTNOTUM
	SCHEMBL1355904	0.80	SIGMAR1 (0.64)	ABL1SIGMAR1KDM4EMAPK1TSHR
	SCHEMBL1357656	0.79	ABL1 (0.73)	ABL1SIGMAR1KDM4EMAPTNOTUM
	SCHEMBL1356897	0.79	SIGMAR1 (0.75)	ABL1SIGMAR1KDM4ECACNA1GKCNH2
	SCHEMBL1356458	0.78	SIGMAR1 (0.59)	ABL1SIGMAR1KDM4ENOTUMHTT
	SCHEMBL1356900	0.78	SIGMAR1 (0.77)	ABL1SIGMAR1KDM4ECACNA1GKCNH2
	SCHEMBL8473697	0.77	ABL1 (0.53)	ABL1SIGMAR1KDM4EMAPTELOVL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.