⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569538 | 0.77 | KDM4E (0.38) | — | |
| SCHEMBL1628640 | 0.69 | PTGS1 (0.34) | — | |
| SCHEMBL2122059 | 0.67 | — | — | |
| SCHEMBL11445907 | 0.66 | ESR1 (0.35) | — | |
| SCHEMBL659527 | 0.64 | ALDH1A1 (0.39) | — | |
| SCHEMBL10705687 | 0.64 | — | — | |
| SCHEMBL10445564 | 0.64 | — | — | |
| SCHEMBL5460830 | 0.64 | PTGS1 (0.36) | — | |
| SCHEMBL2819365 | 0.63 | — | — | |
| SCHEMBL3662900 | 0.63 | HTT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130244939-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130130979-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130012685-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| US-8304391-B2 | Peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2012-11-06 | — | — | US | disclosed |
| EP-1625156-B1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX INC (US) | 2012-09-19 | — | — | EP | disclosed |
| US-8227422-B2 | Peptides and compounds that bind to a receptor | GLAXOSMITHKLINE LLC (US) | 2012-07-24 | — | — | US | disclosed |
| CN-1966520-B | Peptides and compounds that bind to a receptor | GLAXO WELLCOME INC | 2012-07-11 | — | — | CN | disclosed |
| US-20120157660-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110282029-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| EP-2338897-A1 | Peptides and compounds that bind to a thrombopoietin receptor | GLAXO GROUP LIMITED (GB) | 2011-06-29 | — | — | EP | disclosed |
| US-5773569-A | TREATMENT OF HUMAN DISEASES | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-06-30 | — | — | US | disclosed |
| US-5767234-A | INTERLEUKIN AGONISTS AND ANTAGONISTS; ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; SKIN, LIVER AND RESPIRATORY SYSTEM DISORDERS; IMMUNOLOGY | AFFYMAX TECHNOLOGIES, N.V. (GB) | 1998-06-16 | — | — | US | disclosed |
| US-5683983-A | INHIBITS PRODUCTION AND ACCUMULATION OF EOSINOPHILS; ASTHMA; ANTIINFLAMMATORY,-ARTHRITIC AND ULCER AGENTS; OLIGOPEPTIDES, PEPTIDES AND PEPTIDE MIMETICS | GLAXO GROUP LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| US-5677280-A | INTERLEUKIN ANTAGONIST | GLAXO GROUP LIMITED (GB) | 1997-10-14 | — | — | US | disclosed |
| US-5668110-A | Peptides and compounds that bind to the IL-5 receptor | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-09-16 | — | — | US | disclosed |
| US-5654276-A | RESPIRATORY SYSTEM DISODERS; BINDING OF POLYPEPTIDE TO INTERLEULIN | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-08-05 | — | — | US | disclosed |
| US-5608035-A | Peptides and compounds that bind to the IL-1 receptor | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-03-04 | — | — | US | disclosed |
| WO-1996040749-A1 | COMPOUNDS AND PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | JOHNSON & JOHNSON CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040750-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO A THROMBOPOIETIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 1996-12-19 | — | — | WO | disclosed |
| WO-1995020973-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-1 RECEPTOR | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-08-10 | — | — | WO | disclosed |