Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.32 |
| ▸ | CDK2 | P24941 | 4/20 | 0.32 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.32 |
| ▸ | CDK7 | P50613 | 3/20 | 0.32 |
| ▸ | CCNH | P51946 | 3/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569538 | 0.71 | KDM4E (0.38) | PTPN1 | |
| SCHEMBL11446385 | 0.69 | CYP3A4 (0.34) | ALOX5 | |
| SCHEMBL1356915 | 0.66 | — | — | |
| SCHEMBL11445986 | 0.66 | ESR1 (0.38) | ESR1ESR2CCNE1CDK2CDK1 | |
| SCHEMBL2484255 | 0.61 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL1628640 | 0.60 | PTGS1 (0.34) | — | |
| SCHEMBL29514811 | 0.60 | PTGS1 (0.34) | — | |
| SCHEMBL14283999 | 0.59 | ACHE (0.37) | ESR1ESR2CCNE1CDK2CDK1 | |
| SCHEMBL16900585 | 0.59 | ACHE (0.37) | ESR1ESR2CCNE1CDK2CDK1 | |
| SCHEMBL11705076 | 0.59 | ALOX5 (0.40) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209516-A | Triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4209515-A | Triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4208426-A | Pyranochromone derivatives and therapeutic composition comprising same for treatment of allergic diseases | EISAI CO., LTD. (JP) | 1980-06-17 | — | — | US | disclosed |