Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514811 | 0.80 | PTGS1 (0.34) | CYP3A4 | |
| SCHEMBL1628640 | 0.80 | PTGS1 (0.34) | CYP3A4 | |
| SCHEMBL1356915 | 0.77 | — | — | |
| SCHEMBL29242847 | 0.77 | MAOA (0.33) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL2142826 | 0.76 | PSEN1 (0.34) | PTPN1GAA | |
| SCHEMBL10705687 | 0.75 | — | — | |
| SCHEMBL29242849 | 0.75 | TSHR (0.32) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL3662900 | 0.73 | HTT (0.30) | KDM4EALDH1A1HPGDGAAHIF1A | |
| SCHEMBL11445907 | 0.71 | ESR1 (0.35) | PTPN1 | |
| SCHEMBL29242848 | 0.71 | PSEN1 (0.38) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263946-A1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | HOLLISTER INCORPORATED | 2023-08-24 | — | — | US | claimed |
| EP-4178637-A1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | Hollister Incorporated (US) | 2023-05-17 | — | — | EP | claimed |
| WO-2022015755-A1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | HOLLISTER INCORPORATED (US) | 2022-01-20 | — | — | WO | claimed |
| WO-2012017057-A1 | ADHESIVE COMPOSITION WITH ENHANCED CURE THROUGH VOLUME | LOCTITE (R&D) LIMITED (IE) | 2012-02-09 | — | — | WO | claimed |
| US-20230263946-A1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | HOLLISTER INCORPORATED | 2023-08-24 | — | — | US | disclosed |
| EP-2679580-B1 | THIOAMIDE COMPOUND, METHOD FOR PRODUCING THIOAMIDE COMPOUND, METHOD FOR PRODUCING [(4R,6R)-6-AMINOETHYL-1,3-DIOXAN-4-YL]ACETATE DERIVATIVE, AND METHOD FOR PRODUCING ATORVASTATIN | MICROBIAL CHEM RES FOUND (JP) | 2017-08-09 | — | — | EP | disclosed |
| CN-103384659-B | Thioamide compound and produce the method for this compound, [(4R, 6R)-6-aminoethyl-1,3-dioxane-4-yl] acetic ester derivative and atorvastatin | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-25 | — | — | CN | disclosed |
| US-8785690-B2 | Thioamide compound, method for producing thioamide compound, method for producing [(4R,6R)-6-aminoethyl-1,3-dioxan-4-yl]acetate derivative, and method for producing atorvastatin | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20130338375-A1 | Thioamide Compound, Method for Producing Thioamide Compound, Method for Producing [(4R,6R)-6-Aminoethyl-1,3-Dioxan-4-YL]Acetate Derivative, and Method for Producing Atorvastatin | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-12-19 | — | — | US | disclosed |
| CN-103384659-A | Thioamide compound, method for producing thioamide compound, method for producing [(4r,6r)-6-aminoethyl-1,3-dioxane-4-yl]acetate derivative, and method for producing atorvastatin | MICROBIAL CHEM RES FOUND | 2013-11-06 | — | — | CN | disclosed |
| WO-2012017057-A1 | ADHESIVE COMPOSITION WITH ENHANCED CURE THROUGH VOLUME | LOCTITE (R&D) LIMITED (IE) | 2012-02-09 | — | — | WO | disclosed |
| EP-2125017-A2 | MODULATION OF NEUROGENESIS WITH USE OF MODAFINIL | Braincells, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008083204-A2 | MODULATION OF NEUROGENESIS BY MELATONINERGIC LIGANDS | BRAINCELLS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| EP-1940389-A2 | MODULATION OF NEUROGENESIS BY PDE INHIBITION | Braincells, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1928437-A2 | NEUROGENESIS BY MUSCARINIC RECEPTOR MODULATION | Braincells, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2008030651-A1 | COMBINATIONS CONTAINING A 4-ACYLAMINOPYRIDINE DERIVATIVE | BRAINCELLS, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2007134136-A2 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007134077-A2 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007047978-A2 | MODULATION OF NEUROGENESIS BY PDE INHIBITION | BRAINCELLS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007025177-A2 | NEUROGENESIS BY MUSCARINIC RECEPTOR MODULATION | BRAINCELLS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338375-A1 | Thioamide Compound, Method for Producing Thioamide Compound, Method for Producing [(4R,6R)-6-Aminoethyl-1,3-Dioxan-4-YL]Acetate Derivative, and Method for Producing Atorvastatin | HMGCR, CYP4A11, NR1H3 | KDM4E 3903/4885ALDH1A1 1232/4885CYP3A4 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.