Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.53 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743802 | 0.89 | MEN1 (0.68) | MEN1TSHRKMT2AHCRTR2HCRTR1 | |
| SCHEMBL13570607 | 0.86 | HTR1A (0.57) | MEN1TSHRKMT2AHTR1AHTR7 | |
| SCHEMBL14664076 | 0.86 | TSHR (0.64) | MEN1TSHRKMT2AHCRTR2HCRTR1 | |
| SCHEMBL14828703 | 0.86 | MEN1 (0.64) | MEN1TSHRKMT2AHCRTR2HCRTR1 | |
| SCHEMBL13570470 | 0.82 | SPHK1 (0.47) | MEN1TSHRKMT2ADGAT2HTR1A | |
| SCHEMBL30524755 | 0.81 | SLC6A9 (0.47) | MEN1TSHRKMT2ADGAT2SPHK2 | |
| SCHEMBL845312 | 0.79 | GAA (0.60) | MEN1TSHRKMT2AHCRTR2HCRTR1 | |
| SCHEMBL3070982 | 0.78 | HTT (0.54) | TSHRKMT2AHTR1AHTR7HTT | |
| SCHEMBL30524878 | 0.78 | VNN1 (0.45) | MEN1TSHRKMT2ANPSR1HTR1A | |
| SCHEMBL19475146 | 0.77 | MEN1 (0.53) | MEN1TSHRKMT2AHCRTR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | claimed |