Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845518 | 0.92 | GAA (0.52) | GAAPABPC1TSHRKMT2AMEN1 | |
| SCHEMBL872930 | 0.91 | GAA (0.52) | GAAPABPC1TSHRKMT2AMEN1 | |
| SCHEMBL845284 | 0.89 | MAPK1 (0.58) | GAAPABPC1KMT2AMEN1LMNA | |
| SCHEMBL845005 | 0.89 | KDM4E (0.54) | GAAPABPC1TSHRKDM4ELMNA | |
| SCHEMBL845021 | 0.86 | ALDH1A1 (0.53) | GAAPABPC1TSHRKDM4ELMNA | |
| SCHEMBL845007 | 0.86 | PABPC1 (0.49) | GAAPABPC1KMT2AMEN1KDM4E | |
| SCHEMBL845131 | 0.86 | PABPC1 (0.49) | GAAPABPC1KMT2AMEN1KDM4E | |
| SCHEMBL845301 | 0.86 | PABPC1 (0.51) | GAAPABPC1TSHRKMT2AMEN1 | |
| SCHEMBL845285 | 0.85 | GAA (0.48) | GAAPABPC1KDM4ELMNAMAPK1 | |
| SCHEMBL845305 | 0.85 | GAA (0.58) | GAAPABPC1TSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| EP-1893573-B1 | INHIBITORS OF HCV REPLICATION | BRISTOL MYERS SQUIBB CO (US) | 2010-07-21 | — | — | EP | disclosed |