Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437305 | 0.88 | ALDH1A1 (0.55) | F2ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL6437308 | 0.88 | ALDH1A1 (0.55) | F2ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL6980126 | 0.87 | AGTR2 (0.52) | DPP4 | |
| SCHEMBL8536863 | 0.86 | DPP4 (0.49) | F2DPP4RAB9AERAP2ERAP1 | |
| SCHEMBL15743824 | 0.86 | F2 (0.51) | F2DPP4ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL15743844 | 0.86 | F2 (0.51) | F2DPP4ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL31376320 | 0.86 | DPP4 (0.65) | F2DPP4RAB9AERAP2ERAP1 | |
| SCHEMBL13570424 | 0.84 | VNN1 (0.50) | F2 | |
| SCHEMBL14828684 | 0.83 | F2 (0.52) | F2DPP4ACE | |
| SCHEMBL14828681 | 0.83 | F2 (0.52) | F2DPP4ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | disclosed |